Cholesterol levels and heart health
Since all animal cells
manufacture cholesterol, all animal-based foods contain cholesterol in varying amounts. Dietary sources of cholesterol include cheese, egg yolks, beef, pork, poultry, fish, and
prawns. However dietary cholesterol intake does not correlate well
with blood plasma cholesterol levels.
There is a correlation between saturated
fat intake and cholesterol levels
but most of the circulating plasma level
of cholesterol is made by
our own liver.
Cholesterol is
essential for our bodies. It is
in every cell membrane, is needed to make
hormones, bile acids for digestion and for synthesising vitamin D. It is transported by lipoproteins we know as HDL and LDL .
Most of the cholesterol in our
bodies is produced
in the liver with dietary cholesterol adding to this. The amount absorbed by the body depends on how much is
available from the diet. The biosynthesis of cholesterol is
directly regulated by the cholesterol levels present. A
higher intake from food leads to a decrease in production, whereas a lower intake from food has the opposite effect. Most
evidence shows
that low HDL cholesterol is
a risk factor for cardiovascular events.
Some people are genetically
predisposed
to high cholesterol levels.
Low density lipoprotein (LDL) carries cholesterol to the cells that need it, but if there’s too much cholesterol for the cells
to
use it, it can build up in artery
walls contributing to disease
of the arteries; for this reason, LDL is known
as “bad cholesterol”.
Recent evidence is pointing to links
between Alzheimer’s and cholesterol. Lack of certain nutrients can aggravate this process.
High Density Lipoprotein (HDL) particles transport
cholesterol back to the liver, either for excretion or for other tissues that
synthesise hormones. Large numbers
of HDL particles correlates with better health outcomes. HDL can remove
cholesterol from the macrophages of the arterial wall. Thus increased concentrations of HDL correlate with lower rates of atheroma and HDL is sometimes referred to as “good cholesterol”. Better levels of HDL are associated with lower levels of inflammatory
markers.
The Lipid Hypothesis-
new insights.
The work of Ancel Keys,
an American physiologist, led to ‘the lipid hypothesis’ which links raised blood cholesterol levels to the occurrence of heart disease.
An accumulation of evidence
resulted in the acceptance of the lipid hypothesis by most of the medical
community; however, a growing minority argues that the evidence does not support it, and that mechanisms
independent of blood cholesterol levels are responsible. This debate is referred to as the “cholesterol controversy”. It is
closely related to the saturated
fat and cardiovascular disease
controversy. More evidence
is pointing towards the danger of
excess sugar and carbohydrate consumption as many high fat consuming communities do not have cardiovascular
problems. Importantly they do not consume sugar or refined carbs. Norway and Innuit peoples are amongst them. Many more
studies are ongoing.
5mmol/L or less for healthy
adults
4mmol/L or less for those at high risk
As a general guide, LDL levels should be:
3mmol/L or less for healthy
adults
2mmol/L or less for those at high
risk
NHS Guidelines
An ideal level of HDL is
above 1mmol/L. A lower level of HDL can increase your
risk of heart disease.
Your ratio of total cholesterol to HDL may also
be calculated. This is
your total cholesterol level divided
by your HDL level. Generally, this ratio should be below 4, as a higher ratio increases your risk
of heart disease.
To summarise
recent studies , Protective foods
Oily fish
Raw nuts and seeds
Plant polyphenols and plant based foods
Anti inflammatory foods
Anti oxidants
Fibre
Olive oil
Damaging foods /diets
Oils -Excess Omega 6
: Omega 3 ratio. Vegetable oils Trans fats- these are processed
hydrogenated margarines
etc
Red meat
Processed meats
High carb and sugar foods
Typical western diet
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